Alzheimer’s disease is the most common form of dementia. Research shows that people with Alzheimer’s have a different microbiome than healthy people. Certain bacteria and bacterial substances are found more often in the brains of deceased Alzheimer’s patients than in healthy brains. This indicates that the gut microbiome influences the development of this condition.

Chronic inflammation of the lungs. About 10-30% of asthma patients also have abdominal complaints. A reduced diversity and different composition of the gut and lung microbiome is also seen. Research into the so-called gut-lung axis is still young and in full development, but there is increasing evidence that the gut microbiome plays a role in asthma.

Arteriosclerosis causing narrowing of the coronary arteries. This leads to a reduction or shutdown of the blood supply. Inflammatory responses involved in atherosclerosis are influenced by the microbiome.

Autism spectrum disorder is an information processing disorder in the brain. Characteristic are limitations in social interaction, communication and behavior. In autistic children, abnormalities in the microbiome have been found and it has been found that they more often have a ‘leaky gut’: an increased permeability of the intestinal wall.

Autoimmune diseases arise because the immune system sees the body’s own cells and substances as foreign. The body will then produce antibodies against healthy cells of its own. The cause for this lies at least partly in the microbiome. Changes in this give the wrong stimulus to the immune system. Molecular mimicry plays a role in this: bacterial substances that resemble the body’s own substances.

A chronic inflammation of the lining of the colon. In this condition, there is something drastically wrong in the interaction between the immune system and the microbiome, and the composition of the microbiome affects that. Adjusting this by probiotics or poo transplantation seems to improve the complaints.

Thin, unformed stools that cannot be controlled can develop suddenly (acute) but can also be a long-term complaint or disorder (chronic). Research shows that adjusting the microbiome with probiotics can reduce the symptoms of diarrhea.

A combination of related complaints and symptoms, of which chronic fatigue is the most important. The microbiome of patients appears to be different from healthy individuals. In addition, there are indications that there are bacterial substances in the blood of patients to which the immune system is known to react violently. This is probably related to an increased permeability of the intestinal wall.

Collection of more than 50 diseases in which the brain can no longer process information properly. People with Alzheimer’s, the most common form of dementia, have a different microbiome than healthy people. Certain bacterial substances are found more often in the brains of deceased patients than in healthy brains. This indicates that the gut microbiome influences the development of this condition.

A mental illness that affects people’s feelings, thoughts and mood. People who are depressed are depressed for a long time and hardly feel like doing anything. They often lose interest in the things around them and can no longer really enjoy themselves. Depression is when the feelings of dejection last for at least two weeks. This also includes a lack of motivation.

Abnormalities in the composition of the microbiome have been found in patients with depression. Another striking difference from healthy persons is an increased blood level of a specific short-chain fatty acid (valeric acid). This substance is produced by the microbiome, can cross the blood-brain barrier, and can affect brain functions.

Metabolic disease in which the body can no longer maintain the blood sugar level, resulting in damage (risk) in the heart, eyes, kidneys and feet. In type 2 diabetes, increased inflammation and insulin resistance play a role, and the microbiome influences this. The microbiome of diabetics is different from that of healthy individuals.

Persistent pain, especially in the muscles, tendons and ligaments. Therefore also called ‘soft tissue rheumatism’. The cause of this is unknown. It is striking that a large to very large proportion of fibromyalgia patients (30-75%) also have IBS (irritable bowel) complaints. In addition, there are indications that there is bacterial disturbance in the small intestine in fibromyalgia patients.

Generic term for diseases of the heart or blood vessels. Well-known cardiovascular diseases are myocardial infarction, stroke, heart spasm and shop window legs. Inflammatory responses involved in the development of atherosclerosis are influenced by the microbiome.

Hypertension, too high a force with which the blood is pumped through the blood vessels. We speak of high blood pressure when the upper pressure is higher or equal to 140 mmHg and / or the lower pressure is higher or equal to 90 mmHg.

In patients with high blood pressure, the composition and diversity of the microbiome appears to differ from that of healthy persons. Moreover, laboratory animals have been found to develop high blood pressure after a ‘poo transplant’ of patients with high blood pressure. Studies with probiotics have found an improved lowered blood pressure in patients.

The collective name for two intestinal disorders: Crohn’s disease (chronic inflammation of the entire digestive tract) and ulcerative colitis (inflammation of the colon)

In these conditions, there is something drastically wrong in the interaction between the immune system and the microbiome, and the composition of the microbiome influences this. Adjusting this by probiotics or poo transplantation seems to improve the complaints.

COPD stands for Chronic Obstructive Pulmonary Disease. The lungs are damaged, breathing becomes more difficult and patients have less energy.

It is striking that approximately 50% of COPD patients have abdominal complaints. Patients with irritable bowel syndrome (IBS, IBS) also have a 50% higher chance of COPD. Conversely, COPD patients have an almost 2 times higher risk of inflammatory bowel disease (IBD). As with asthma, the so-called gut-lung axis probably plays a role. The various indications indicate that the gut microbiome plays a role in COPD.

Metabolic disorder, manifested by a combination of high cholesterol, high blood pressure, obesity (especially increase in the abdomen) and high blood sugar. A relationship with the microbiome has been demonstrated in all these factors and an increased inflammatory value in the body plays a role. This is influenced by the Microbiome.

Disease in which the protective and insulating layer around the nerves in the brain, spinal cord and optic nerves (the central nervous system) is damaged. This can cause problems with walking, feeling and seeing, among other things.

In MS patients, differences are found in the composition of the microbiome, the most striking difference being that MS patients have fewer bacteria that can dampen autoimmune reactions.

Obesity, substantial overweight. Differences in the microbiome are found in obese people compared to lean people. These microbiome abnormalities diminish as patients lose weight (regardless of diet).

10 to 15% of the Dutch have IBS complaints. Symptoms are abdominal pain, gas and an abnormal bowel pattern: constipation, diarrhea or both.

People with an irritable bowel often have a reduced diversity and altered composition of the microbiome. An irritable bowel often develops after an intestinal infection or after using antibiotics.

Chronic inflammation of joints that leads to pain and stiffness in joints or muscles. There is chronic inflammation.

The gut microbiome plays a crucial role in the coordination of the immune system, and thus in the degree to which the immune system is ‘on’. In addition, changes are found in the microbiome of both the oral cavity and the intestine. Studies with probiotics show improvements in quality of life and pain score.

SIBO, which stands for Small Intestinal Bacterial Overgrowth, is a condition characterized by an excessive growth of bacteria in the small intestine. This can lead to symptoms such as bloating, abdominal pain, and irregular bowel movements. SIBO shares many similarities with Irritable Bowel Syndrome (IBS). The treatment of SIBO focuses on alleviating symptoms and restoring balance in the gut. This can be achieved through dietary adjustments and eating habits, as well as the use of specific probiotics and fibers that support gut health. The diagnosis of SIBO is based on your symptoms and test results. While a stool test can provide indications, a breath test often offers more clarity about the presence of SIBO.

Chronic inflammation throughout the digestive tract. In this condition, there is something drastically wrong in the interaction between the immune system and the microbiome, and the composition of the microbiome affects that. Adjusting this by means of probiotics or poo transplantation seems to improve the symptoms, although the indications are less strong than with ulcerative colitis.