Advice-help and product information update
After some technical challenges, all descriptions and references of the supplements and masterful ingredients have now been completely completed. You can find this by clicking on the (i) next to a product or ingredient in the Advice Help or on the Recipe Creation page. The description provides a summary of all studies that have been done with the product or ingredient in question, including the corresponding references.
The Advice Help has also been further improved. The proposed amounts of the magisterial ingredients now also take into account the minimum and maximum daily doses for each ingredient. What has not changed is that the outcome of the Advisory Help is based on the completed scores for the various indications (complaints, medical background, and lab results) on the one hand and on the strength of the evidence of the products/ingredients for these indications on the other. The new version of the Advisory Aid also includes a more refined gradation of the strength of the evidence, which is weighted in a systematic (GRADE-inspired way [1]). We are currently working hard to make the evidence scores visible to you in the next version of the Advice Aid, so that you can see even better what the advice is based on.
Probiotics may be useful for depression
For several years now, it has become clear that the microbiome plays a role in moods and depression; There is talk of the gut-brain axis. There are relationships with the quality of life cq. depression and the composition, structure, and function of the microbiome [2,3]. Feces transplantation from patients with major depression disorder (MDD) to mice or rats results in behaviors associated with depression [4,5]. Clinical studies have shown that interventions with probiotics can reduce depression [6-8].
Royal interest in the microbiome
On Tuesday 26 November, the Palace Symposium 'The Microbiome' took place, attended by King Willem-Alexander and Princess Beatrix [9]. Speakers were Martin Blaser, director of the Human Microbiome Program, and Professor Max Nieuwdorp, internist-endocrinologist and pioneer in faecal transplant research. Both readings can be listened to [9]. The importance of the microbiome for health is now also being paid attention to at the highest level.
References
- https://en.wikipedia.org/wiki/The_Grading_of_Recommendations_Assessment,_Development_and_Evaluation_(GRADE)_approach
- https://doi.org/10.1002/bies.201800027
- https://doi.org/10.1038/s41564-018-0337-x
- https://doi.org/10.1038/mp.2016.44
- https://doi.org/10.1016/j.jpsychires.2016.07.019
- https://doi.org/10.1016/j.nut.2015.09.003
- https://doi.org/10.29219/fnr.v62.1218
- https://doi.org/10.1016/j.clnu.2018.04.010
- https://www.paleisamsterdam.nl/paleissymposium/paleissymposium-the-microbiome/