{"id":227395,"date":"2026-08-06T15:27:45","date_gmt":"2026-08-06T13:27:45","guid":{"rendered":"https:\/\/microbiome-center.nl\/?p=227395"},"modified":"2026-08-06T15:27:51","modified_gmt":"2026-08-06T13:27:51","slug":"20-probiotics-with-anxiety-and-tension","status":"publish","type":"post","link":"https:\/\/microbiome-center.nl\/en\/20-probiotics-with-anxiety-and-tension\/","title":{"rendered":"20: Probiotics with anxiety and tension"},"content":{"rendered":"<style id=\"divi-off-canvas-hide-on-load\">\n[data-interaction-target=\"zwocqpy6qf\"] { display: none !important; }\n<\/style>\n\n<p class=\"wp-block-paragraph\"><strong>Probiotics with anxiety and tension<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">We recently added the Lactiplantibacillus plantarum P-8 to our portfolio. A well-conducted RCT shows that this strain is effective against anxiety and tension (1). The same study also found evidence for an effect against stress, albeit slightly less strong (1). That this probiotic has a beneficial effect on anxiety and tension fits with the growing body of research showing that the microbiome plays a role in anxiety, tension, and depression (2) and that probiotics can improve this (3). It is suspected that this effect has to do with, among other things, the influence of the microbiome and probiotics on inflammatory activity (2.4). Anti-inflammatory effects have also been seen in L. plantarum P-8 in studies with the single strain or in combination with other strains (1,5,6). There is also evidence in animal models that this strain has an effect on oxidative stress (7.8), an aspect that is also associated with anxiety, tension and depression (9,10). Finally, it is interesting that research with L. plantarum P-8 shows that this strain can increase secretory IgA (11,12), as it is known that stress can lead to decreased sIgA excretion (13). It can be concluded that the microbiome influences multiple mechanisms involved in anxiety and tension and that probiotics can modulate this.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Further evidence and information about this strain can be found in the description of this ingredient in our system.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>References:<\/strong><\/p>\n\n\n\n<ol start=\"1\" class=\"wp-block-list\">\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.clnu.2018.09.010\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1016\/j.clnu.2018.09.010<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.cpr.2020.101943\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1016\/j.cpr.2020.101943<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.neubiorev.2019.03.023\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1016\/j.neubiorev.2019.03.023<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1002\/jnr.24476\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1002\/jnr.24476<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1007\/s00394-020-02437-4\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1007\/s00394-020-02437-4<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1111\/1751-7915.13661\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1111\/1751-7915.13661<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1007\/s00394-020-02437-4\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1007\/s00394-020-02437-4<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.3390\/ani10040548\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/ani10040548<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1080\/10715762.2018.1475733\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1080\/10715762.2018.1475733<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.4161\/oxim.2.2.7944\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.4161\/oxim.2.2.7944<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.nut.2013.11.018\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1016\/j.nut.2013.11.018<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.intimp.2015.07.024\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1016\/j.intimp.2015.07.024<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.3389\/fnint.2013.00086\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3389\/fnint.2013.00086<\/a><\/li>\n<\/ol>\n<div class=\"et_pb_section_0 et_pb_section et_pb_section--fixed et_section_regular et_flex_section et-interaction-target-zwocqpy6qf preset--module--divi-section--default\" data-interaction-trigger=\"7hv7hq8l9z\" data-interaction-target=\"zwocqpy6qf\" id=\"video_canvas\"><div class=\"et_pb_row_0 et_pb_row et_flex_row\"><div class=\"et_pb_column_0 et_pb_column et-last-child et_flex_column et_pb_css_mix_blend_mode_passthrough et_flex_column_24_24 et_flex_column_24_24_tablet et_flex_column_24_24_phone\"><div class=\"et_pb_icon_0 et_pb_icon et_pb_module et_flex_module video_close\"><span class=\"et_pb_icon_wrap\"><span class=\"et-pb-icon\">\uf057<\/span><\/span><\/div><div class=\"et_pb_code_0 et_pb_code et_pb_module\" id=\"microbiome_center_video_iframe\"><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Probiotics with anxiety and tension We recently added the Lactiplantibacillus plantarum P-8 to our portfolio. A well-conducted RCT shows that this strain is effective against anxiety and tension (1). The same study also found evidence for an effect against stress, albeit slightly less strong (1). That this probiotic has a beneficial effect on anxiety and [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[16],"tags":[],"doelgroep":[106],"class_list":["post-227395","post","type-post","status-publish","format-standard","hentry","category-uncategorized","doelgroep-practitioner"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>20: Probiotics with anxiety and tension - Microbiome Center<\/title>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"20: Probiotics with anxiety and tension - Microbiome Center\" \/>\n<meta property=\"og:description\" content=\"Probiotics with anxiety and tension We recently added the Lactiplantibacillus plantarum P-8 to our portfolio. A well-conducted RCT shows that this strain is effective against anxiety and tension (1). The same study also found evidence for an effect against stress, albeit slightly less strong (1). 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