{"id":227358,"date":"2026-08-06T13:31:07","date_gmt":"2026-08-06T11:31:07","guid":{"rendered":"https:\/\/microbiome-center.nl\/?p=227358"},"modified":"2026-08-06T14:43:34","modified_gmt":"2026-08-06T12:43:34","slug":"9-migraine-lgg-namechange-lactobacillus","status":"publish","type":"post","link":"https:\/\/microbiome-center.nl\/en\/9-migraine-lgg-namechange-lactobacillus\/","title":{"rendered":"9: Migraine, LGG, namechange Lactobacillus"},"content":{"rendered":"<style id=\"divi-off-canvas-hide-on-load\">\n[data-interaction-target=\"zwocqpy6qf\"] { display: none !important; }\n<\/style>\n\n<p class=\"wp-block-paragraph\"><strong>Probiotics for migraine<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">There are several indications of a relationship between the gut microbiome and migraine (1). A recent systematic review of placebo-controlled studies found two studies that met the inclusion criteria, one of which found a fairly large effect and the other no effect of probiotics (2). It is also known from experience that migraine patients sometimes benefit greatly from probiotics. Some patients who have tried everything report that their migraine attacks have virtually disappeared after they start taking probiotics. A nice example of a study that describes this type of observations in more than 1000 patients is this one, in which the severity of the complaints decreased considerably (3).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>New strain: LGG<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A new strain has been added to the prescribing portfolio of probiotics: Lacticaseibacillus rhamnosus GG, the world\u2019s most researched probiotic bacterial strain. If you are wondering if there is a spelling mistake in the last name, read the last message in this knowledge flash. The fact that this strain, also known as LGG, has been researched so much (over 1,100 publications in PubMed), certainly doesn\u2019t mean it\u2019s effective for everything. For example, a frequently researched indication is eczema, but a meta-analysis of RCTs shows that the LGG is not effective in this regard (4). We have of course added the LGG because there are various indications where it is effective. In fact, the LGG achieves the highest achievable score for acute diarrhea in our GRADE-based rating system due to two meta-analyses of RCTs with very consistent results (5,6). There is also strong evidence that the LGG is effective in IBS (7.8). Interestingly, LGG has also been studied in ADHD and mania, although these are only preliminary indications (9,10). In addition, there are various other indications, which you can find in the information on our website.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Name change of the bacterial genus Lactobacillus<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A few months ago, a team of international experts changed the name of the bacterial genus Lactobacillus (11). This genus contained several known bacterial species, such as L. acidophilus, L. rhamnosus, and L. brevis. For some time there had been indications from, among other things, genetic analyzes that the taxonomic heterogeneity within the old Lactobacillus genus was too great to reasonably group all 261 bacterial species. In the new classification, 23 new genera have been introduced, all of which start with the letter L, so that abbreviations do not change. There are various websites with an overview in which the old and new names can be looked up (12).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>References<\/strong>:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><a href=\"https:\/\/doi.org\/10.1186\/s10194-020-1078-9\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1186\/s10194-020-1078-9<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.3390\/jcm8091441\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/jcm8091441<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1007\/s15006-018-1052-5\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1007\/s15006-018-1052-5<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.3390\/nu10091319\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/nu10091319<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.3748\/wjg.v25.i33.4999\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3748\/wjg.v25.i33.4999<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1111\/apt.15267\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1111\/apt.15267<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1111\/j.1365-2036.2011.04665.x\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1111\/j.1365-2036.2011.04665.x<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1097\/MCG.0000000000001054\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1097\/MCG.0000000000001054<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1038\/pr.2015.51\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1038\/pr.2015.51<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1111\/bdi.12652\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1111\/bdi.12652<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1099\/ijsem.0.004107\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1099\/ijsem.0.004107<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.microbiometimes.com\/the-lactobacillus-taxonomy-change-has-arrived-what-do-you-need-to-know\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.microbiometimes.com\/the-lactobacillus-taxonomy-change-has-arrived-what-do-you-need-to-know\/<\/a><\/li>\n<\/ol>\n<div class=\"et_pb_section_0 et_pb_section et_pb_section--fixed et_section_regular et_flex_section et-interaction-target-zwocqpy6qf preset--module--divi-section--default\" data-interaction-trigger=\"7hv7hq8l9z\" data-interaction-target=\"zwocqpy6qf\" id=\"video_canvas\"><div class=\"et_pb_row_0 et_pb_row et_flex_row\"><div class=\"et_pb_column_0 et_pb_column et-last-child et_flex_column et_pb_css_mix_blend_mode_passthrough et_flex_column_24_24 et_flex_column_24_24_tablet et_flex_column_24_24_phone\"><div class=\"et_pb_icon_0 et_pb_icon et_pb_module et_flex_module video_close\"><span class=\"et_pb_icon_wrap\"><span class=\"et-pb-icon\">\uf057<\/span><\/span><\/div><div class=\"et_pb_code_0 et_pb_code et_pb_module\" id=\"microbiome_center_video_iframe\"><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Probiotics for migraine There are several indications of a relationship between the gut microbiome and migraine (1). A recent systematic review of placebo-controlled studies found two studies that met the inclusion criteria, one of which found a fairly large effect and the other no effect of probiotics (2). It is also known from experience that [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[16],"tags":[],"doelgroep":[106],"class_list":["post-227358","post","type-post","status-publish","format-standard","hentry","category-uncategorized","doelgroep-practitioner"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>9: Migraine, LGG, namechange Lactobacillus - Microbiome Center<\/title>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"9: Migraine, LGG, namechange Lactobacillus - Microbiome Center\" \/>\n<meta property=\"og:description\" content=\"Probiotics for migraine There are several indications of a relationship between the gut microbiome and migraine (1). A recent systematic review of placebo-controlled studies found two studies that met the inclusion criteria, one of which found a fairly large effect and the other no effect of probiotics (2). 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