{"id":227134,"date":"2026-07-28T12:02:08","date_gmt":"2026-07-28T10:02:08","guid":{"rendered":"https:\/\/microbiome-center.nl\/3-nutrition-intestines-and-osteoporosis\/"},"modified":"2026-08-06T10:51:56","modified_gmt":"2026-08-06T08:51:56","slug":"3-nutrition-intestines-and-osteoporosis","status":"publish","type":"post","link":"https:\/\/microbiome-center.nl\/en\/3-nutrition-intestines-and-osteoporosis\/","title":{"rendered":"3: Diet, gut and osteoporosis"},"content":{"rendered":"<style id=\"divi-off-canvas-hide-on-load\">\n[data-interaction-target=\"zwocqpy6qf\"] { display: none !important; }\n<\/style>\n\n<p class=\"wp-block-paragraph\"><strong>The response to food is highly individual<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The macronutrient composition of food appears to explain only 16-32% of the glucose response to food, individual factors such as the composition, function and structure of the microbiome are much more decisive. This is evident from the PREDICT-1 study that intensively followed more than 1000 twins and non-twins (<a href=\"https:\/\/doi.org\/10.1093\/cdn\/nzz037.OR31-01-19\">https:\/\/doi.org\/10.1093\/cdn\/nzz037.OR31-01-19<\/a>, see the full presentation here).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Irritable Bowel Syndrome (IBS) improves with probiotics and glutamine<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Probiotics relieve pain and overall symptom score in IBS (IBS), concludes a meta-analysis of RCTs. However, the effectiveness does depend on the composition (<a href=\"https:\/\/doi.org\/10.3748\/wjg.v21.i10.3072\">https:\/\/doi.org\/10.3748\/wjg.v21.i10.3072<\/a>). In many cases there is also increased intestinal permeability with IBS, especially when diarrhea is in the foreground. In those cases, glutamine appears to be effective in IBS (<a href=\"https:\/\/gut.bmj.com\/content\/68\/6\/996\">https:\/\/gut.bmj.com\/content\/68\/6\/996<\/a>).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Probiotics may be helpful in osteoporosis<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The microbiome plays an important role in the gut-bone axis. Animal studies provide first evidence that probiotics have a protective effect against osteoporosis (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5710820\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5710820\/<\/a>). In elderly people with bone fractures, supplementation with probiotics also leads to faster healing of bones and less pain (<a href=\"http:\/\/doi.org\/10.3920\/BM2016.0067\">http:\/\/doi.org\/10.3920\/BM2016.0067<\/a>).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n<div class=\"et_pb_section_0 et_pb_section et_pb_section--fixed et_section_regular et_flex_section et-interaction-target-zwocqpy6qf preset--module--divi-section--default\" data-interaction-trigger=\"7hv7hq8l9z\" data-interaction-target=\"zwocqpy6qf\" id=\"video_canvas\"><div class=\"et_pb_row_0 et_pb_row et_flex_row\"><div class=\"et_pb_column_0 et_pb_column et-last-child et_flex_column et_pb_css_mix_blend_mode_passthrough et_flex_column_24_24 et_flex_column_24_24_tablet et_flex_column_24_24_phone\"><div class=\"et_pb_icon_0 et_pb_icon et_pb_module et_flex_module video_close\"><span class=\"et_pb_icon_wrap\"><span class=\"et-pb-icon\">\uf057<\/span><\/span><\/div><div class=\"et_pb_code_0 et_pb_code et_pb_module\" id=\"microbiome_center_video_iframe\"><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>The response to food is highly individual The macronutrient composition of food appears to explain only 16-32% of the glucose response to food, individual factors such as the composition, function and structure of the microbiome are much more decisive. This is evident from the PREDICT-1 study that intensively followed more than 1000 twins and non-twins [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[16],"tags":[],"doelgroep":[106],"class_list":["post-227134","post","type-post","status-publish","format-standard","hentry","category-uncategorized","doelgroep-practitioner"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>3: Diet, gut and osteoporosis - Microbiome Center<\/title>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"3: Diet, gut and osteoporosis - Microbiome Center\" \/>\n<meta property=\"og:description\" content=\"The response to food is highly individual The macronutrient composition of food appears to explain only 16-32% of the glucose response to food, individual factors such as the composition, function and structure of the microbiome are much more decisive. 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