{"id":225543,"date":"2026-06-26T12:16:23","date_gmt":"2026-06-26T10:16:23","guid":{"rendered":"https:\/\/microbiome-center.nl\/medici\/case-report\/"},"modified":"2026-06-26T12:16:25","modified_gmt":"2026-06-26T10:16:25","slug":"case-report","status":"publish","type":"page","link":"https:\/\/microbiome-center.nl\/en\/medici\/case-report\/","title":{"rendered":"#Case Report"},"content":{"rendered":"<style id=\"divi-off-canvas-hide-on-load\">\n[data-interaction-target=\"zwocqpy6qf\"] { display: none !important; }\n<\/style>\n<div class=\"et_pb_section_0 et_pb_section et_section_regular et_flex_section preset--module--divi-section--default\">\n<div class=\"et_pb_row_0 et_pb_row et_flex_row\">\n<div class=\"et_pb_column_0 et_pb_column et-last-child et_flex_column et_pb_css_mix_blend_mode_passthrough et_flex_column_24_24 et_flex_column_24_24_tablet et_flex_column_24_24_phone\">\n<div class=\"et_pb_heading_0 et_pb_heading et_pb_module et_flex_module\"><div class=\"et_pb_heading_container\"><h1 class=\"et_pb_module_header\">Case reports from practice<\/h1><\/div><\/div>\n\n<div class=\"et_pb_text_0 et_pb_text et_pb_bg_layout_light et_pb_module et_flex_module\"><div class=\"et_pb_text_inner\"><p>Within the Microbiome Center, practical cases are regularly discussed during intervision meetings. By sharing experiences, treatment strategies and outcomes with each other, affiliated practitioners continue to learn from each other. <\/p>\n<p>We develop the most valuable and instructive cases into a case report. Here you will find a selection of practical examples in which the starting situation, treatment and results are described. <\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<div class=\"et_pb_section_1 et_pb_section et_section_regular et_flex_section preset--module--divi-section--default\">\n<div class=\"et_pb_row_1 et_pb_row et_flex_row\">\n<div class=\"et_pb_column_1 et_pb_column et-last-child et_flex_column et_pb_css_mix_blend_mode_passthrough et_flex_column_24_24 et_flex_column_24_24_tablet et_flex_column_24_24_phone\">\n<div class=\"et_pb_accordion_0 et_pb_accordion et_pb_module et_flex_module\">\n<div class=\"et_pb_accordion_item_0 et_pb_accordion_item et_pb_toggle et_pb_module et_pb_toggle_open et_flex_module\"><h4 class=\"et_pb_toggle_title\">Acne<\/h4><div class=\"et_pb_toggle_content et_flex_module\"><p>On May 30, we gave an interesting webinar about the relationship between the skin and the intestine. Something you will probably encounter regularly in practice. In the webinar, this beautiful case came up from one of our affiliated doctors that we do not want to withhold from you. Eva is 32 years old and has suffered from acne for 16 years and also suffered from recurrent vaginal yeast infections. Several dermatological treatments have had no effect. She also suffers from fatigue and various hormonal complaints. She has been adjusting her diet to a diet that is low in carbohydrates for some time and she does not eat sugars, unfortunately this has had no effect on her symptoms. This photo shows her skin before the treatment.       <\/p>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" class=\"wp-image-12974 alignnone size-full\" src=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-Acne-afb1.jpg\" alt=\"\" width=\"224\" height=\"279\"><\/p>\n<p>&nbsp;<\/p>\n<p>Her microbiome shows a diversity of 6 and a dysbiosis index of 20, a good amount of butyrate-producing bacteria but a significant overgrowth of Klebsiella, Enterobacter, Serratia and Pseudomonas, and a slight increase in Candida Parapslilosis and no evidence of inflammation or leaky gut.<\/p>\n<p>The treatment consisted of \u2022 MyOwnBlend with the following ingredients:<\/p>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" class=\"wp-image-12971 alignnone size-full\" src=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-Acne-afb2.jpg\" alt=\"\" width=\"261\" height=\"274\"><\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>And vitD, linidol, magnesium, Omega3, silybum-curcuma, lypogold (enzymes), Kandillon<\/li>\n<\/ul>\n<p>Nothing was changed in her diet.<\/p>\n<p>After 6 weeks it goes very well, almost all her complaints have disappeared, she is no longer tired, wakes up rested, no longer has vaginal complaints and her skin looks radiant, even in the months that follow it continues to go well. The measurement shows an impressive decrease in the (potentially) pathogenic bacteria. <\/p>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" class=\"wp-image-12968 alignnone size-full\" src=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-Acne-afb3.jpg\" alt=\"\" width=\"222\" height=\"295\"><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Response of attending physician Roos Quadekker:  <\/strong><\/p>\n<p>I am impressed by the positive result. A great example of how personalized microbiome therapy can contribute to improving total health. And also nice to see how sustainable the change is and that after this therapy the body can maintain homeostasis again. In the spotlight: <em>The Lacticaseibacillus rhamnosus <\/em>SP1 is known to reduce acne, probably because it acts on insulin resistance<sup>1. <\/sup> In addition, this strain is also used to improve oral health and to support the breakdown of gluten.   <\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"list-style-type: none;\">\n<ol>\n<li><sup>Fabbrocini, G. et al. Beneficial Microbes 7, 625\u2013630 (2016) <\/sup><\/li>\n<\/ol>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><sup> <\/sup>This is of course what we do it for as a Microbiome Center, but also you as a practitioner. In practice, we see that 72% of people who use a MyOwnBlend show a good or very good result, and we can increase this percentage by learning more about the treatment results of our patients together. We build up that knowledge together, you as a practitioner by using our platform, the patient by sharing his results, and we by analyzing them and returning this knowledge to the system. We want to share an inspiring case with you every month. If you have a case of your own and would like to share it for learning in inspiration, please contact us!    <\/p>\n<\/div><\/div>\n\n<div class=\"et_pb_accordion_item_1 et_pb_accordion_item et_pb_toggle et_pb_module et_pb_toggle_close et_flex_module\"><h4 class=\"et_pb_toggle_title\">Autism<\/h4><div class=\"et_pb_toggle_content et_flex_module\"><p><strong><span class=\"fontstyle0\">Microbiome Therapy in Autism<\/span><\/strong><\/p>\n<p><span class=\"fontstyle2\">Fila (6 years old), from a Bulgarian family, was registered with a diagnosis of autism spectrum disorder (ASD) made in April 2024 at the University Hospital Frankfurt. She suffered daily from a bloated belly, urge to eat (especially carbohydrates\/sugar), no feeling of satiety, restless behavior, abnormal bowel patterns and could not speak \u2013 only make sounds. There were frequent toilet visits with little output, widely varying stool consistency, and suspicions of systemic and neurological imbalances. At the start she used a.o. Omni-Biotic 9 and Gilalia.   <\/span><\/p>\n<p>&nbsp;<\/p>\n<p><strong><span class=\"fontstyle0\">Diagnostics<\/span><\/strong> <span class=\"fontstyle2\">Highly disturbed diversity (low Shannon index) and increased dysbiosis index<\/span> <span class=\"fontstyle2\">Increased intestinal permeability (including increased zonulin and secretory IgA) Overgrowth of potentially pathogenic species<\/span><\/p>\n<p><span class=\"fontstyle2\">Microbiome analysis April 2024: clear abnormalities<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" class=\"wp-image-12965 alignnone size-medium\" src=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-Autisme-afb1-514x300.jpg\" alt=\"\" width=\"514\" height=\"300\"> <img decoding=\"async\" class=\"wp-image-12962 alignnone size-medium\" src=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-Autisme-afb2-617x300.jpg\" alt=\"\" width=\"617\" height=\"300\"><\/p>\n<p>&nbsp;<\/p>\n<p><strong><span class=\"fontstyle0\">Treatment and build-up<\/span><\/strong><\/p>\n<p><span class=\"fontstyle2\">After analysis, the following was started: <\/span> <span class=\"fontstyle2\">- MyOwnBlend (customized preparation with LGG, Bifidobacterium, prebiotics, anti-inflammatory substances, among others)<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" class=\"wp-image-12959 alignnone size-full\" src=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-Autisme-afb3.jpg\" alt=\"\" width=\"305\" height=\"214\"><\/p>\n<p>&nbsp;<\/p>\n<p><strong><span class=\"fontstyle0\">Clinical effect within 4 weeks<\/span><\/strong><br \/><span class=\"fontstyle2\">- Bloated belly disappeared <\/span><br \/><span class=\"fontstyle2\">- Stool stabilized (2\u20133 times a day, less variable) <\/span><br \/><span class=\"fontstyle2\">- Balance and calmer behavior <\/span><br \/><span class=\"fontstyle2\">- Onset of speech development <\/span><br \/><span class=\"fontstyle2\">- Neurological examination confirmed clinical improvement<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><strong><span class=\"fontstyle0\">Course and follow-up research<\/span><\/strong><\/p>\n<p><span class=\"fontstyle2\">During the summer\/autumn 2024: <\/span><br \/><span class=\"fontstyle2\">- Mother reports: less skin complaints, more calmness, improved adaptation <\/span><br \/><span class=\"fontstyle2\">- Started with Lunafini in September <\/span><br \/><span class=\"fontstyle2\">- Clear improvement visible on EEG scan compared to October 2023<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" class=\"wp-image-12956 alignnone size-medium\" src=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-Autisme-afb4-482x300.jpg\" alt=\"\" width=\"482\" height=\"300\"><\/p>\n<p>&nbsp;<\/p>\n<p><strong><span class=\"fontstyle0\">Second microbiome analysis fall 2024<\/span><\/strong><br \/><span class=\"fontstyle2\">- Overgrowth potential pathogens disappeared<\/span><br \/><span class=\"fontstyle2\">- Still increased intestinal permeability<\/span><\/p>\n<p><strong><span class=\"fontstyle0\">Second phase MyOwnBlend<\/span><\/strong><\/p>\n<p><span class=\"fontstyle2\">New composition from December 2024: <\/span><br \/><span class=\"fontstyle2\">- LGG, S. boulardii, Akkermansia, PHGG, 2'-FL <\/span><br \/><span class=\"fontstyle2\">- First reaction: soft, smelly stools \u2192 dosage adjusted Within a few days, the balance was restored and Fila did not get any infections, despite her mother being seriously ill.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><strong><span class=\"fontstyle0\">Winter 2024\/2025: Language Development and Cognitive Gains<\/span><\/strong> <span class=\"fontstyle2\">- Fila Began to Understand Questions and Consider Answers <\/span> <span class=\"fontstyle2\">- Better Memory and Learning Ability <\/span> <span class=\"fontstyle2\">- She Can Now Retain Information, Which She Couldn't Do Before<\/span> <span class=\"fontstyle2\"> - \"She's calm, everything is going well,\" says her mother<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" class=\"wp-image-12953 alignnone size-medium\" src=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-Autisme-afb5-730x204.jpg\" alt=\"\" width=\"730\" height=\"204\"><\/p>\n<p>&nbsp;<\/p>\n<p><strong><span class=\"fontstyle0\">Conclusion: microbial modulation as a risk in ASD<\/span><\/strong><\/p>\n<p><span class=\"fontstyle2\">Fila is an example of how targeted microbiome therapy, based on extensive analysis, can reduce not only gastrointestinal complaints but also behavioral and<\/span> <span class=\"fontstyle2\">can positively influence neurological symptoms in children with autism. In children with GI complaints and autism, treating the microbiome is a promising and substantiated intervention route. <\/span> <span class=\"fontstyle2\">Questions about this case or about the use of MyOwnBlend in autism? Feel free to contact the Microbiome Center. We like to think along in clinically complex situations.  <\/span><\/p>\n<p><strong><span class=\"fontstyle0\">New ingredient with evidence for effect on autism<\/span><\/strong><\/p>\n<p><span class=\"fontstyle2\">A small study with a formulation where the probiotic strain <\/span><span class=\"fontstyle4\">Lacticaseibacillus paracasei <\/span> <span class=\"fontstyle2\">Lpc-37 part of was, shows some beneficial effect on autism. If you score for autism in the advice help, this strain can be part of the advice (depending on which other indications have been scored). <\/span><\/p>\n<p>&nbsp;<\/p>\n<p><strong><span class=\"fontstyle0\">Webinar Autism<\/span><\/strong> <span class=\"fontstyle2\">Missed the webinar on autism? This can be viewed at the   <\/span><a href=\"https:\/\/microbiome-center.nl\/en\/videos_medisch\/\"><span class=\"fontstyle2\">Videos <\/span><\/a><span class=\"fontstyle2\">on our website<\/span><\/p>\n<\/div><\/div>\n\n<div class=\"et_pb_accordion_item_2 et_pb_accordion_item et_pb_toggle et_pb_module et_pb_toggle_close et_flex_module\"><h4 class=\"et_pb_toggle_title\">Histamine<\/h4><div class=\"et_pb_toggle_content et_flex_module\"><p><strong><span class=\"fontstyle0\">Histamine and SIBO \u2013 a breakthrough in treatment!<\/span><\/strong><\/p>\n<p><span class=\"fontstyle2\">We get a lot of questions about histamine, both from patients and practitioners, which is why we recently devoted an extensive webinar to it.  <\/span><\/p>\n<p><span class=\"fontstyle2\">One of the cases discussed was this:<\/span> <span class=\"fontstyle2\">A 39-year-old man had been struggling <\/span><span class=\"fontstyle2\">with <\/span><strong><span class=\"fontstyle3\">chronic abdominal complaints<\/span><\/strong> <strong><span class=\"fontstyle3\">since childhood <\/span><\/strong><span class=\"fontstyle2\">, fatigue, headaches, mental overstimulation, chronic nasal congestion and OSAS. Despite various investigations, a solution was not forthcoming. <\/span> <strong><span class=\"fontstyle0\">Diagnostics<\/span><\/strong> <span class=\"fontstyle2\">A <\/span><strong><span class=\"fontstyle3\">SIBO breath test <\/span><\/strong><span class=\"fontstyle2\">showed <\/span><strong><span class=\"fontstyle3\">hydrogen SIBO<\/span><\/strong><span class=\"fontstyle2\">, and microbiome analysis showed <\/span><strong><span class=\"fontstyle3\">increased inflammatory markers, increased intestinal permeability, increased anti-gliadin antibodies, extremely high histamine levels<\/span><span class=\"fontstyle2\">.<\/span><\/strong><\/p>\n<p><span class=\"fontstyle3\">Results 13-04-2024:<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" class=\"wp-image-12950 alignnone size-medium\" src=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-Histamine-afb1-403x300.jpg\" alt=\"\" width=\"403\" height=\"300\"><\/p>\n<p><img decoding=\"async\" class=\"wp-image-12947 alignnone \" src=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-Histamine-afb2.jpg\" alt=\"\" width=\"413\" height=\"123\"><\/p>\n<p>&nbsp;<\/p>\n<p><strong><span class=\"fontstyle0\">Approach & treatment:<\/span><\/strong><\/p>\n<ul>\n<li><strong><span class=\"fontstyle3\">Dietary intervention<\/span><\/strong><span class=\"fontstyle2\"><strong>:<\/strong> elimination of gluten and sugars, increased protein intake.<\/span><\/li>\n<li><strong><span class=\"fontstyle3\">2 weeks of Elemental Diet <\/span><\/strong><span class=\"fontstyle2\">followed by <\/span><strong><span class=\"fontstyle3\">MyOwnBlend <\/span><\/strong><span class=\"fontstyle2\">and digestive enzymes.<\/span><\/li>\n<\/ul>\n<p><strong><span class=\"fontstyle0\">Results after 3 months:<\/span><\/strong><\/p>\n<p><span class=\"fontstyle1\">\u2705 <\/span><span class=\"fontstyle3\">SIBO solved <\/span> <\/p>\n<p><span class=\"fontstyle3\"><span class=\"fontstyle1\">\u2705<\/span>Histamine fully normalized  <\/span><\/p>\n<p><span class=\"fontstyle3\"><span class=\"fontstyle1\">\u2705 <\/span>Complaints greatly reduced <\/span><span class=\"fontstyle2\">(no abdominal pain, better nasal breathing, more energy, less headaches) <\/span> <\/p>\n<p><span class=\"fontstyle1\">\u2705 <\/span><span class=\"fontstyle3\">More than 10 kg weight loss<\/span> <span class=\"fontstyle3\">Results 01-07-2024:<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" class=\"wp-image-12944 alignnone size-medium\" src=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-Histamine-afb3-372x300.jpg\" alt=\"\" width=\"372\" height=\"300\"><\/p>\n<p>&nbsp;<\/p>\n<p><strong><span class=\"fontstyle0\">Webinar Histamine<\/span><\/strong><\/p>\n<p><span class=\"fontstyle2\">Missed the webinar on histamine? This can be viewed at the   <\/span><a href=\"https:\/\/microbiome-center.nl\/en\/videos_medisch\/\"><span class=\"fontstyle2\">Videos <\/span><\/a><span class=\"fontstyle2\">on our website<\/span><\/p>\n<\/div><\/div>\n\n<div class=\"et_pb_accordion_item_3 et_pb_accordion_item et_pb_toggle et_pb_module et_pb_toggle_close et_flex_module\"><h4 class=\"et_pb_toggle_title\">Depression<\/h4><div class=\"et_pb_toggle_content et_flex_module\"><p><strong><span class=\"fontstyle0\">The role of the gut microbiome in psychological complaints: a successful case study<\/span><\/strong><\/p>\n<p><span class=\"fontstyle2\">Did you know that the gut microbiome plays a crucial role in brain and psyche health? A disturbed gut microbiome can contribute to psychological symptoms such as depression, anxiety and fatigue. At the Microbiome Center, we see every day how personalized microbiome treatments can make a decisive difference.  <\/span><\/p>\n<p><strong><span class=\"fontstyle3\">A special case<\/span><\/strong><\/p>\n<p><span class=\"fontstyle2\">Erik (23 years old) had been struggling <\/span><span class=\"fontstyle0\">for 10 years <\/span> <span class=\"fontstyle2\">with serious mood problems, sleeping problems, headaches, stomach aches and loss of energy. Despite several consultations with medical specialists, the cause remained unclear and the complaints persistent. It became impossible for him to continue his studies. He was now     <\/span><span class=\"fontstyle0\">was diagnosed <\/span><span class=\"fontstyle2\">with <\/span><span class=\"fontstyle0\">bipolar disorder<\/span><span class=\"fontstyle2\">, but due to the long waiting time of <\/span><span class=\"fontstyle0\">six months<\/span>, <span class=\"fontstyle2\">he started microbiome treatment in the meantime <\/span><span class=\"fontstyle0\"><\/span><span class=\"fontstyle2\">. During a  <\/span><span class=\"fontstyle0\">Microbiome analysis  <\/span><span class=\"fontstyle2\">we discovered signs of SIBO and a strongly disturbed intestinal flora. Erik received a   <\/span><span class=\"fontstyle0\">tailored treatment <\/span><span class=\"fontstyle2\">with MyOwnBlend, including probiotics, PHGG (fiber) and other targeted elements.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" class=\"wp-image-12940 alignnone size-medium\" src=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-Depressie-afb1-1-247x300.jpg\" alt=\"\" width=\"247\" height=\"300\"><\/p>\n<p>&nbsp;<\/p>\n<p><strong><span class=\"fontstyle3\">The result?<\/span><\/strong><\/p>\n<ul>\n<li><strong><span class=\"fontstyle0\">Sleep pattern restored<\/span><\/strong><span class=\"fontstyle2\"><strong>:<\/strong> from 15 to 8 hours per night.<\/span><\/li>\n<li><strong><span class=\"fontstyle0\">Energy level<\/span><\/strong><span class=\"fontstyle2\"><strong>:<\/strong> from 10-20 to 70-80 on a scale of 0-100.<\/span><\/li>\n<li><strong><span class=\"fontstyle0\">Abdominal complaints: <\/span><\/strong><span class=\"fontstyle2\">completely disappeared.<\/span><\/li>\n<li><strong><span class=\"fontstyle0\">Allergic reactions: <\/span><\/strong><span class=\"fontstyle2\">gone.<\/span><\/li>\n<li><strong><span class=\"fontstyle0\">Mood: <\/span><\/strong><span class=\"fontstyle2\">significantly improved (from 1 to 8 on a scale of 10)<\/span><\/li>\n<\/ul>\n<p><span class=\"fontstyle2\">Erik was able to resume his studies with pleasure and now experiences enough energy to cope with his daily activities. Both Erik and his mother are convinced that without this microbiome treatment, his complaints would not have been resolved. <\/span><\/p>\n<p>&nbsp;<\/p>\n<p><strong><span class=\"fontstyle3\">What does this mean for your practice?<\/span><\/strong><\/p>\n<p><span class=\"fontstyle2\">This case once again underlines the strong link between the gut microbiome and the psyche. Targeted microbiome analysis and personalized therapies offer new leads for the treatment of both   <\/span><span class=\"fontstyle0\">physical <\/span><span class=\"fontstyle2\">and <\/span><span class=\"fontstyle0\">psychological complaints<\/span><span class=\"fontstyle2\">.<\/span> <span class=\"fontstyle2\">Do you have questions about personalized microbiome treatments or how you can support your patients in this? Please feel free to contact us! <\/span><\/p>\n<p>&nbsp;<\/p>\n<p><strong><span class=\"fontstyle3\">Depression Webinar<\/span><\/strong><\/p>\n<p><span class=\"fontstyle2\">Missed the webinar on depression? This can be viewed at the   <\/span><a href=\"https:\/\/microbiome-center.nl\/en\/videos_medisch\/\"><span class=\"fontstyle2\">Videos <\/span><\/a><span class=\"fontstyle2\">on our website<\/span><\/p>\n<\/div><\/div>\n\n<div class=\"et_pb_accordion_item_4 et_pb_accordion_item et_pb_toggle et_pb_module et_pb_toggle_close et_flex_module\"><h4 class=\"et_pb_toggle_title\">Vaginal Probiotics Ovules<\/h4><div class=\"et_pb_toggle_content et_flex_module\"><p><strong><span class=\"fontstyle0\">Positive Experiences with Vaginal Probiotics Ovules<\/span><\/strong><\/p>\n<p><span class=\"fontstyle2\">The vaginal microbiome has a completely different character than the gut microbiome, where, for example, a very low diversity is seen as healthy. A healthy vaginal microbiome is dominated by one of four Lactobacillus bacterial species, in which the dominance of   <\/span><span class=\"fontstyle3\">L. crispatus  <\/span><span class=\"fontstyle2\">associated with health. Over the past two years, we have gained extensive experience using our vaginal probiotic ovules. We have received numerous positive responses from users who have benefited from this treatment for a variety of vaginal conditions, such as candida, bacterial vaginosis, and even fertility issues.  <\/span> <span class=\"fontstyle2\">Below we would like to share the experience of one of our affiliated doctors, who has tried the ovules himself.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><strong><span class=\"fontstyle0\">User experience<\/span><\/strong><\/p>\n<p><span class=\"fontstyle4\">Profile: <\/span><span class=\"fontstyle2\">Woman, 40 years old, doctor<\/span> <span class=\"fontstyle4\">Complaint: <\/span><span class=\"fontstyle2\">Recurrent fungal infections, where she preferred not to use medication<\/span> <span class=\"fontstyle4\">Treatment: <\/span><span class=\"fontstyle2\">Prescribed vaginal ovules to herself<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><strong><span class=\"fontstyle0\">Her findings:<\/span><\/strong><\/p>\n<p><span class=\"fontstyle5\">\"The symptoms of itching and crumbly discharge disappeared very quickly. I used the ovules for over a week, and then I stopped during my period. Then I used one ovule twice, right after my period. This has ensured that to date both the candida and an unpleasant odor stay away. So I would definitely recommend the ovules.\"<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><strong><span class=\"fontstyle0\">Product information: Vaginal Probiotics Ovules<\/span><\/strong><\/p>\n<p><span class=\"fontstyle2\">Our vaginal ovules contain three active strains:<\/span><br \/><strong><span class=\"fontstyle4\">- <\/span><span class=\"fontstyle5\">L. crispatus <\/span><span class=\"fontstyle4\">SP28 <\/span><\/strong><span class=\"fontstyle2\">(2.5x10\u2079 cfu\/ovule)<\/span><br \/><strong><span class=\"fontstyle4\">- <\/span><span class=\"fontstyle5\">L. crispatus <\/span><span class=\"fontstyle4\">LCR01 <\/span><\/strong><span class=\"fontstyle2\">(2.5x10\u2079 cfu\/ovule)<\/span><br \/><strong><span class=\"fontstyle4\">- <\/span><span class=\"fontstyle5\">L. acidophilus <\/span><span class=\"fontstyle4\">La02 <\/span><\/strong><span class=\"fontstyle2\">(2.5x10\u2079 cfu\/ovule)<\/span><\/p>\n<p><span class=\"fontstyle2\">The matrix of the ovule is composed of cocoa butter and coconut butter, which ensures optimal application.<\/span> <span class=\"fontstyle4\">Availability:  <\/span><span class=\"fontstyle2\">Available in packs of 30 vaginal ovules for \u20ac88,-. A leaflet with clear instructions is included. <\/span><\/p>\n<p><img decoding=\"async\" class=\"wp-image-12934 alignnone size-medium\" src=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-Vaginale-Ovules-afb1-269x300.jpg\" alt=\"\" width=\"269\" height=\"300\" srcset=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-Vaginale-Ovules-afb1-269x300.jpg 269w, https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-Vaginale-Ovules-afb1.jpg 461w\" sizes=\"(max-width: 269px) 100vw, 269px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><strong><span class=\"fontstyle0\">Order or more information?<\/span><\/strong> <span class=\"fontstyle2\">Feel free to contact us or visit our website for more details.<\/span><\/p>\n<\/div><\/div>\n\n<div class=\"et_pb_accordion_item_5 et_pb_accordion_item et_pb_toggle et_pb_module et_pb_toggle_close et_flex_module\"><h4 class=\"et_pb_toggle_title\">SIBO<\/h4><div class=\"et_pb_toggle_content et_flex_module\"><p>SIBO stands for \"Small Intestinal Bacterial Overgrowth\", the presence of too many bacteria in the small intestine that cause complaints. Very common and difficult to treat. <\/p>\n<p>&nbsp;<\/p>\n<p><strong>Therefore, here is a practical example.<\/strong><\/p>\n<p>This 52-year-old woman came to the doctor's office with skin complaints, itchy spots on arms, legs and torso, which were present in one place for days to weeks and then reappeared in another place. In addition, she was very tired. Her symptoms arose after she had received a double course of antibiotics due to a Lyme infection. Upon inquiry, it turned out that she also had problems with her intestines, she regularly felt very bloated and had variable, somewhat hard and laborious, greasy, sticky stools. She was a yoga teacher, had a nice job in healthcare that she could no longer practice due to her fatigue, had a healthy diet with lots of vegetables and a little fish and meat. She did notice that she could no longer tolerate dairy well, which caused an increase in her abdominal complaints. Her microbiome analysis showed the following: Diversity 6, dysbiosis index 18, PH 6.9 Low levels of enterococci and lactobacilli, high fat content and increased zonulin.      <\/p>\n<p>&nbsp;<\/p>\n<h2><img decoding=\"async\" class=\"wp-image-12931 alignnone size-full\" style=\"color: #666666; font-size: 14px;\" src=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-SIBO-afb1.jpg\" alt=\"\" width=\"366\" height=\"249\"><\/h2>\n<p><strong>Personalized treatment<\/strong><\/p>\n<p>Due to a strong suspicion of SIBO, the treatment was focused on that, but also on her specific health problems and complaints: bloating, fatigue, slightly leaky gut, etc. She was prescribed a MyOwnBlend containing the following ingredients:<\/p><\/blockquote>\n<blockquote><p><img decoding=\"async\" class=\"wp-image-12928 alignnone size-medium\" src=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-SIBO-afb2-310x300.jpg\" alt=\"\" width=\"310\" height=\"300\"><\/p><\/blockquote>\n<blockquote><p>She used this according to the thermos bottle method: at the end of the day, dissolve the daily dosage for the next day in a thermos flask lukewarm (37gr) water, let it stand overnight and drink it in bits at a time during the next day. For example, the bacteria have already taken action, they already produce active metabolites such as lactate and acetate, and they are immediately active at the time of ingestion. <\/p>\n<p>&nbsp;<\/p>\n<p><strong>Follow-up<\/strong><\/p>\n<p>Her skin complaints disappeared in three weeks, see the photos before and after below:<\/p><\/blockquote>\n<blockquote><p><img decoding=\"async\" class=\"wp-image-12925 alignnone size-full\" src=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-SIBO-afb3.jpg\" alt=\"\" width=\"235\" height=\"237\">      <img decoding=\"async\" class=\"wp-image-12922 alignnone size-full\" src=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-SIBO-afb4.jpg\" alt=\"\" width=\"232\" height=\"234\"><\/p><\/blockquote>\n<blockquote><p>She no longer suffered from a surprised feeling and had neat stools once a day (BSC 3-4). But more importantly, she had her energy back and could go back to work. The post-measurement also showed a nice improvement: Diversity 5, dysbiosis index 17, PH 6.5  <\/p><\/blockquote>\n<blockquote><p><img decoding=\"async\" class=\"wp-image-12919 alignnone size-full\" src=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-SIBO-afb5.jpg\" alt=\"\" width=\"340\" height=\"186\"><\/p>\n<p><strong>Diagnostics<\/strong><\/p><\/blockquote>\n<blockquote><p>To make the diagnosis of SIBO, you have 3 pillars:<\/p>\n<ul>\n<li>Symptoms (bloated and tired after eating, fluctuating greasy sticky stools)<\/li>\n<li>SIBO breath test (see Biovis)<\/li>\n<li>Indications in the faeces analysis, namely an increased PH, low amount of lactobacilli and\/or enterococci, increased zonulin, a lot of fat in the stool.<\/li>\n<\/ul>\n<p><strong>Featured<\/strong><\/p>\n<p>The treatment of SIBO can be challenging, complaints are sometimes difficult to treat and often recur. And standard probiotics often have the opposite effect. Strains that usually have a better effect are the bacillus strains (spore formers), the <em>Saccharomyces boulardii<\/em> and the <em>Enterococcus faecium<\/em>. The prebiotic PHGG is one of the few fibers that is usually well tolerated. By filling in the advice help and giving it a high score at SIBO, these ingredients often come to the fore.    <\/p><\/blockquote>\n<blockquote><p><img decoding=\"async\" class=\"wp-image-12916 alignnone size-full\" src=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-SIBO-afb6.jpg\" alt=\"\" width=\"604\" height=\"161\" srcset=\"https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-SIBO-afb6.jpg 604w, https:\/\/microbiome-center.nl\/wp-content\/uploads\/2025\/06\/Casus-Report-SIBO-afb6-480x128.jpg 480w\" sizes=\"(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) 604px, 100vw\" \/><\/p><\/blockquote>\n<blockquote><p>In addition, every patient has their own health problems and complaints, and it is important to include them in the approach, in order to maximize the chance of success. It is also important to look for the cause of the complaints, because if this can be removed, you increase the chance of recovery. In this case, the cause was the course of antibiotics, a one-off severe disturbance, so after restoring the balance in the microbiome, the symptoms stayed away. But the causes of SIBO can be very diverse. In addition to the MyOwnBlend, you can of course give additional advice:    <\/p>\n<ul>\n<li>Not eating too many times in a day (intermittent fasting)<\/li>\n<li>Restrict carbohydrates \/ limit fodmaps<\/li>\n<li>Digestive enzymes, herbs such as Berberine, and very important: possibly. supplement deficiencies caused by digestive problems (e.g. B12).<\/li>\n<\/ul>\n<p><strong>Response from attending physician Karin Pijper<\/strong><\/p>\n<p>What makes this such an impressive case for me is that she was already doing everything right (no stress, sufficient exercise, healthy food), but after those antibiotics she was so disrupted. And that she did nothing else in the treatment than take the MyOwnBlend, which also made her symptoms disappear in a very short time. Not only her intestinal complaints, but also her fatigue and skin complaints. And it has helped me to recognize SIBO images better.   <\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><div class=\"et_pb_section_2 et_pb_section et_pb_section--fixed et_section_regular et_flex_section et-interaction-target-zwocqpy6qf preset--module--divi-section--default\" data-interaction-trigger=\"7hv7hq8l9z\" data-interaction-target=\"zwocqpy6qf\" id=\"video_canvas\"><div class=\"et_pb_row_2 et_pb_row et_flex_row\"><div class=\"et_pb_column_2 et_pb_column et-last-child et_flex_column et_pb_css_mix_blend_mode_passthrough et_flex_column_24_24 et_flex_column_24_24_tablet et_flex_column_24_24_phone\"><div class=\"et_pb_icon_0 et_pb_icon et_pb_module et_flex_module video_close\"><span class=\"et_pb_icon_wrap\"><span class=\"et-pb-icon\">\uf057<\/span><\/span><\/div><div class=\"et_pb_code_0 et_pb_code et_pb_module\" id=\"microbiome_center_video_iframe\"><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":6,"featured_media":0,"parent":2627,"menu_order":30,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"doelgroep":[106],"class_list":["post-225543","page","type-page","status-publish","hentry","doelgroep-practitioner"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - 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