{"id":225763,"date":"2026-06-26T16:57:04","date_gmt":"2026-06-26T14:57:04","guid":{"rendered":"https:\/\/microbiome-center.nl\/aandoeningen\/healthy-ageing-aging\/"},"modified":"2026-06-30T21:32:42","modified_gmt":"2026-06-30T19:32:42","slug":"healthy-ageing-aging","status":"publish","type":"aandoeningen","link":"https:\/\/microbiome-center.nl\/en\/aandoeningen\/healthy-ageing-aging\/","title":{"rendered":"Healthy ageing, aging"},"content":{"rendered":"<style id=\"divi-off-canvas-hide-on-load\">\n[data-interaction-target=\"zwocqpy6qf\"] { display: none !important; }\n<\/style>\n<div class=\"et_pb_section_0 et_pb_section et_section_regular et_flex_section preset--module--divi-section--default\">\n<div class=\"et_pb_row_0 et_pb_row et_flex_row\">\n<div class=\"et_pb_column_0 et_pb_column et-last-child et_flex_column et_pb_css_mix_blend_mode_passthrough et_flex_column_24_24 et_flex_column_24_24_tablet et_flex_column_24_24_phone\">\n<div class=\"et_pb_heading_0 et_pb_heading et_pb_module et_flex_module\"><div class=\"et_pb_heading_container\"><h1 class=\"et_pb_module_header\">Healthy ageing, aging<\/h1><\/div><\/div>\n\n<div class=\"et_pb_text_0 et_pb_text et_pb_bg_layout_light et_pb_module et_flex_module\"><div class=\"et_pb_text_inner\"><p><span data-metadata=\"<!--(figmeta)eyJmaWxlS2V5IjoiN2RYaVBJUWFIeFVVYUdZVllKZTdpNSIsInBhc3RlSUQiOjY3NjY2NTU1MSwiZGF0YVR5cGUiOiJzY2VuZSIsImVudmlyb25tZW50Ijoid3d3LmZpZ21hLmNvbSIsInNlbGVjdGVkTm9kZURhdGEiOiIzNTA3OjQzNjF8MzF8MCJ9Cg==(\/figmeta)-->\" style=\"caret-color: #000000; color: #000000;\"><\/span>Impression of the publications on the relevance of the microbiome<\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<div class=\"et_pb_section_1 et_pb_section et_section_regular et_flex_section preset--module--divi-section--default\">\n<div class=\"et_pb_row_1 et_pb_row et_grid_row\">\n<div class=\"et_pb_column_1 et_pb_column et_flex_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_text_1 et_pb_text et_pb_bg_layout_light et_pb_module et_flex_module\"><div class=\"et_pb_text_inner\"><p>It is almost by definition unthinkable to grow old healthily without a healthy microbiome. How far does scientific knowledge about the connections extend? <\/p>\n<\/div><\/div>\n<\/div>\n\n<div class=\"et_pb_column_2 et_pb_column et_flex_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_text_2 et_pb_text et_pb_bg_layout_light et_pb_module et_flex_module\"><div class=\"et_pb_text_inner\"><p>Healthy ageing is a topic that is receiving more and more attention, because it is becoming clear that attention to fighting diseases alone is insufficient: although we are getting older, we have not yet succeeded in delaying or preventing diseases (1). For this reason, attention is now being paid to the biology behind the aging process itself and the hypothesis is that it can also delay the onset and progression of diseases (1). <br \/>In a large number of diseases, age is one of the most important risk factors. Given the suspected role of the microbiome in many of these diseases and conditions, such as obesity, metabolic syndrome, type 2 diabetes, cardiovascular disease, and neurodegenerative diseases such as multiple sclerosis, Parkinson's, and Alzheimer's (see separate sections), abnormalities of the microbiome appear to be one of the underlying processes that plays a role in these age-related diseases.<br \/>It is therefore striking that the diversity of the microbiome decreases with age, and that the degree of decline is correlated with the decline in health (2,3). Conversely, there are indications that greater presence of subgroups of bacteria associated with health plays a role in achieving high and very high ages (2,3). There are also indications that the microbiome in the elderly is less stable, while conversely there is a relationship between the composition of the microbiome and the degree of 'brittleness' of the elderly (4). Studies on the use of probiotics in the elderly show cautiously positive results on intestinal complaints, infections, and lung complaints (3,5).    <\/p>\n<\/div><\/div>\n<\/div>\n\n<div class=\"et_pb_column_3 et_pb_column et-last-child et_flex_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_heading_1 et_pb_heading et_pb_module et_flex_module\"><div class=\"et_pb_heading_container\"><h2 class=\"et_pb_module_header\">References<\/h2><\/div><\/div>\n\n<div class=\"et_pb_text_3 et_pb_text et_pb_bg_layout_light et_pb_module et_flex_module\"><div class=\"et_pb_text_inner\"><p>1. Kaeberlein M, Rabinovitch PS, Martin GM. Healthy aging: the ultimate preventative medicine. Science. 2015; 350:1191\u20133.   <\/p>\n<p>2. Calvani R, Picca A, Lo Monaco MR, Landi F, Bernabei R, Marzetti E. Of Microbes and Minds: A Narrative Review on the Second Brain Aging. Front Med [Internet]. 2018 [cited 2018 May 27];5. Available from: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5840854\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5840854\/<\/a>   <\/p>\n<p>3. Vaiserman AM, Koliada AK, Marotta F. Gut microbiota: A player in aging and a target for anti-aging intervention. Ageing Res Rev. 2017; 35:36\u201345. <\/p>\n<p>4. Mello AM, Paroni G, Daragjati J, Pilotto A. Gastrointestinal Microbiota and Their Contribution to Healthy Aging. Dig Dis Basel Switz. 2016; 34:194\u2013201.  <\/p>\n<p>5. Rondanelli M, Giacosa A, Faliva MA, Perna S, Allieri F, Castellazzi AM. Review on microbiota and effectiveness of probiotics use in older. World J Clin Cases WJCC. 2015; 3:156\u201362.   <\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<div class=\"et_pb_section_2 et_pb_section et_section_regular et_flex_section preset--module--divi-section--default\">\n<div class=\"et_pb_row_2 et_pb_row et_flex_row\">\n<div class=\"et_pb_column_4 et_pb_column et-last-child et_flex_column et_pb_css_mix_blend_mode_passthrough et_flex_column_24_24 et_flex_column_24_24_tablet et_flex_column_24_24_phone\">\n<div class=\"et_pb_heading_2 et_pb_heading et_pb_module et_flex_module\"><div class=\"et_pb_heading_container\"><h4 class=\"et_pb_module_header\">Agenda<\/h4><\/div><\/div>\n\n<div class=\"et_pb_heading_3 et_pb_heading et_pb_module et_flex_module\"><div class=\"et_pb_heading_container\"><h2 class=\"et_pb_module_header\">Knowledge & meetings<\/h2><\/div><\/div>\n\n<div class=\"et_pb_text_4 et_pb_text et_pb_bg_layout_light et_pb_module et_flex_module\"><div class=\"et_pb_text_inner\"><p style=\"text-align: center;\">Microbiome Center regularly organizes intervisions, webinars and knowledge meetings for doctors and professionals. The sessions are aimed at both healthcare providers who are orienting themselves on microbiome therapy and experienced practitioners who want to deepen their knowledge.<\/p>\n<\/div><\/div>\n\n<div class=\"et_pb_module et_pb_button_module_wrapper et_pb_button_0_wrapper preset--module--divi-button--default_wrapper\"><a class=\"et_pb_button_0 et_pb_button et_pb_bg_layout_dark et_pb_module et_flex_module button_outline preset--module--divi-button--default\" href=\"https:\/\/microbiome-center.nl\/en\/agenda\/\">View the agenda<\/a><\/div>\n<\/div>\n<\/div>\n<\/div><div class=\"et_pb_section_3 et_pb_section et_pb_section--fixed et_section_regular et_flex_section et-interaction-target-zwocqpy6qf preset--module--divi-section--default\" data-interaction-trigger=\"7hv7hq8l9z\" data-interaction-target=\"zwocqpy6qf\" id=\"video_canvas\"><div class=\"et_pb_row_3 et_pb_row et_flex_row\"><div class=\"et_pb_column_5 et_pb_column et-last-child et_flex_column et_pb_css_mix_blend_mode_passthrough et_flex_column_24_24 et_flex_column_24_24_tablet et_flex_column_24_24_phone\"><div class=\"et_pb_icon_0 et_pb_icon et_pb_module et_flex_module video_close\"><span class=\"et_pb_icon_wrap\"><span class=\"et-pb-icon\">\uf057<\/span><\/span><\/div><div class=\"et_pb_code_0 et_pb_code et_pb_module\" id=\"microbiome_center_video_iframe\"><\/div><\/div><\/div><\/div>","protected":false},"featured_media":0,"template":"","doelgroep":[106],"class_list":["post-225763","aandoeningen","type-aandoeningen","status-publish","hentry","doelgroep-practitioner"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.0 - 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